Circulating Vitamin D Levels and DNA Repair Capacity in Four Molecular

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phylocommons

Stearoyl-CoA Desaturase 1 Activity Determines the Maintenance of DNMT1-Mediated DNA Methylation Patterns in Pancreatic β-Cells

 

Metabolic stress, corresponding to lipotoxicity, impacts the DNA methylation profile in pancreatic β-cells and thus contributes to β-cell failure and the development of sort 2 diabetes (T2D). Stearoyl-CoA desaturase 1 (SCD1) is a rate-limiting enzyme that’s concerned in monounsaturated fatty acid synthesis, which protects pancreatic β-cells towards lipotoxicity. The current research discovered that SCD1 can also be required for the institution and upkeep of DNA methylation patterns in β-cells.

 

  • We confirmed that SCD1 inhibition/deficiency prompted DNA hypomethylation and adjusted the methyl group distribution inside chromosomes in β-cells. Decrease ranges of DNA methylation in SCD1-deficient β-cells have been adopted by decrease ranges of DNA methyltransferase 1 (DNMT1).

 

  • We additionally discovered that the downregulation of SCD1 in pancreatic β-cells led to the activation of adenosine monophosphate-activated protein kinase (AMPK) and a rise within the exercise of the NAD-dependent deacetylase sirtuin-1 (SIRT1). Moreover, the bodily affiliation between DNMT1 and SIRT1 stimulated the deacetylation of DNMT1 beneath circumstances of SCD1 inhibition/downregulation, suggesting a mechanism by which SCD1 exerts management over DNMT1.

 

  • We additionally discovered that SCD1-deficient β-cells that have been handled with compound c, an inhibitor of AMPK, have been characterised by larger ranges of each international DNA methylation and DNMT1 protein expression in contrast with untreated cells.

 

  • Subsequently, we discovered that activation of the AMPK/SIRT1 signaling pathway mediates the impact of SCD1 inhibition/deficiency on DNA methylation standing in pancreatic β-cells. Altogether, these findings recommend that SCD1 is a gatekeeper that protects β-cells towards the lipid-derived lack of DNA methylation and supply mechanistic insights into the mechanism by which SCD1 regulates DNA methylation patterns in β-cells and T2D-relevant tissues.

 

phylocommons
phylocommons

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  • Shipped within 3 weeks.

hsa-mir-100 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097671
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-101 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097673
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-103 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097675
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-105 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097676
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-106a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097677
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-106b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097678
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-107 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097679
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-124 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097680
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-125a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097681
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-127 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097686
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-129 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097689
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-130a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097690
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-130b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097691
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-132 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097692
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-133a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097693
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-133b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097694
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-134 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097695
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-135b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097696
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-137 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097699
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-138 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097700
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-139 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097701
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-140 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097702
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-141 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097703
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-143 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097706
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-145 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097708
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-146a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097709
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-149 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097711
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-150 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097712
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-151 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097714
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-152 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097715
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-153 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097716
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-154 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097717
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-181a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097719
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-181b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097720
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-181c Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097721
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-181d Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097722
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-182 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097723
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-183 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097724
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-184 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097725
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-185 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097726
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-190a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097728
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-190b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097729
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-192 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097731
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-193a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097732
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-193b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097733
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-194 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097734
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-195 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097735
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-197 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097738
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-198 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097739
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-199a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097740
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-199b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097741
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-200a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097742
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-200b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097743
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-202 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097745
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-203 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097746
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-204 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097747
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-205 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097748
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-206 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097749
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-208a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097750
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-208b Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097751
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-211 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097753
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-212 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097754
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-214 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097755
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-215 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097756
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-217 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097757
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-218 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097758
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-219 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097759
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-223 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097764
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-224 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097765
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-298 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097768
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-299 Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097769
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

hsa-mir-320a Real-Time RT-PCR Detection and cel-mir-39-3p Calibration Kit

20-abx097774
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 0
  • 1
  • 2
  • Shipped within 3 weeks.

Circulating Vitamin D Levels and DNA Repair Capacity in Four Molecular Subtypes of Women with Breast Cancer

 

Vitamin D regulates estrogen synthesis amongst different mechanisms concerned in breast most cancers (BC) growth; nonetheless, no proof has been discovered relating to its relationship with DNA restore capability (DRC). Subsequently, the target of this research was to elucidate whether or not DRC ranges are linked with plasma 25(OH)D ranges.

 

  • BC circumstances and controls have been chosen from our BC cohort. DRC ranges have been assessed in lymphocytes by the host-cell reactivation assay. 25(OH)D ranges have been measured utilizing the UniCel DxI 600 Entry Immunoassay System. BC circumstances (n = 91) confirmed larger 25(OH)D ranges than the controls (n = 92) (p = 0.001).

 

  • When stratifying BC circumstances and controls into high and low DRC classes, BC circumstances with low DRC (n = 74) had the best 25(OH)D ranges (p = 0.0001).

 

  • A constructive correlation between 25(OH)D and DRC ranges was discovered for the controls (r = 0.215, p = 0.043) whereas a destructive correlation was discovered for BC circumstances (r = -0.236, p = 0.026). Important variations in 25(OH)D ranges have been noticed when stratifying by molecular subtypes (p = 0.0025).

 

  • Our research supplies proof of a hyperlink between 25(OH)D and DRC in BC together with an outline of to how 25(OH)D ranges fluctuate throughout subtypes. The constructive correlation noticed within the management group means that 25(OH)D contributes in a different way to DRC ranges as soon as the malignancy is developed.

 

Intercourse-specific associations with DNA methylation in lung tissue show smoking interactions

 

Cigarette smoking impacts DNA methylation, however the investigation of sex-specific options of lung tissue DNA methylation in people who smoke has been restricted. Girls seem extra prone to cigarette smoke, and sometimes develop extra extreme lung illness at an earlier age with much less smoke publicity.

 

We aimed to analyse whether or not there are intercourse variations in DNA methylation in lung tissue and whether or not these DNA methylation marks work together with smoking. We collected lung tissue samples from former people who smoke who underwent lung tissue resection. 100 thirty samples from white topics have been included for this evaluation. Regression fashions for intercourse as a predictor of methylation have been adjusted for age, presence of COPD, smoking variables and technical batch variables revealed 710 related websites.

 

294 websites demonstrated sturdy sex-specific methylation associations in foetal lung tissue. Pathway evaluation recognized 6 nominally vital pathways together with the mitophagy pathway. Three CpG websites demonstrated a urged interplay between intercourse and pack-years of smoking: GPR132, ANKRD44 and C19orf60.

 

All of them have been nominally vital in each male- and female-specific fashions, and the impact estimates have been in reverse instructions for female and male; GPR132 demonstrated vital affiliation between DNA methylation and gene expression in lung tissue (P< 0.05). Intercourse-specific associations with DNA methylation in lung tissue are wide-spread and will reveal genes and pathways related to intercourse variations for lung damaging results of cigarette smoking.

 

Orphan GPCR SP9155 Agonist P550 (mouse)

H-5986.1000 1.0mg
EUR 853.00
Description: Sum Formula: C126H195N37O37; CAS# [600171-70-8] net

GPCR GPR86 Antibody

48382-100ul 100ul
EUR 333.00

GPCR GPR86 Antibody

48382-50ul 50ul
EUR 239.00

GPCR RDC1 Antibody

49041-100ul 100ul
EUR 333.00

GPCR RDC1 Antibody

49041-50ul 50ul
EUR 239.00

anti-GPCR GPR3

YF-PA12103 50 ug
EUR 363.00
Description: Mouse polyclonal to GPCR GPR3

anti-GPCR GPR34

YF-PA12105 50 ug
EUR 363.00
Description: Mouse polyclonal to GPCR GPR34

anti-GPCR HM74

YF-PA15914 50 ug
EUR 363.00
Description: Mouse polyclonal to GPCR HM74

anti-GPCR GPR146

YF-PA21926 100 ug
EUR 403.00
Description: Rabbit polyclonal to Anti-GPCR GPR146

anti-GPCR MRGX2

YF-PA22009 50 ug
EUR 363.00
Description: Mouse polyclonal to Anti-GPCR MRGX2

anti-GPCR LOC51210

YF-PA22204 50 ul
EUR 363.00
Description: Mouse polyclonal to GPCR LOC51210

anti-GPCR LOC51210

YF-PA22205 50 ug
EUR 363.00
Description: Mouse polyclonal to GPCR LOC51210

anti-GPCR LOC51210

YF-PA22206 100 ul
EUR 403.00
Description: Rabbit polyclonal to GPCR LOC51210

anti-GPCR LOC51210

YF-PA22207 100 ug
EUR 403.00
Description: Rabbit polyclonal to GPCR LOC51210

anti-GPCR 2037

YF-PA22241 50 ug
EUR 363.00
Description: Mouse polyclonal to Anti-GPCR 2037

anti-GPCR GPR110

YF-PA22867 50 ul
EUR 363.00
Description: Mouse polyclonal to GPCR GPR110

anti-GPCR GPR110

YF-PA22868 50 ug
EUR 363.00
Description: Mouse polyclonal to GPCR GPR110

anti-GPCR GPR3

YF-PA23809 50 ul
EUR 334.00
Description: Mouse polyclonal to GPCR GPR3

anti-GPCR C5L2

YF-PA18412 50 ug
EUR 363.00
Description: Mouse polyclonal to GPCR C5L2

anti-GPCR SALPR

YF-PA18968 50 ul
EUR 363.00
Description: Mouse polyclonal to GPCR SALPR

anti-GPCR GPRC5D

YF-PA19735 50 ug
EUR 363.00
Description: Mouse polyclonal to GPCR GPRC5D

anti-GPCR SALPR

YF-PA26165 50 ul
EUR 334.00
Description: Mouse polyclonal to GPCR SALPR

anti-GPCR EX33

YF-PA26233 50 ul
EUR 334.00
Description: Mouse polyclonal to GPCR EX33

anti-GPCR GPRC5D

YF-PA26334 50 ul
EUR 334.00
Description: Mouse polyclonal to GPCR GPRC5D

anti-GPCR LGR7

YF-PA26522 50 ul
EUR 334.00
Description: Mouse polyclonal to GPCR LGR7

anti-GPCR LGR6

YF-PA26523 50 ul
EUR 334.00
Description: Mouse polyclonal to GPCR LGR6

anti-GPCR TAS1R1

YF-PA26658 50 ul
EUR 334.00
Description: Mouse polyclonal to GPCR TAS1R1

anti-GPCR GPR62

YF-PA26842 50 ul
EUR 334.00
Description: Mouse polyclonal to GPCR GPR62

anti-GPCR LOC51210

YF-PA26875 50 ul
EUR 334.00
Description: Mouse polyclonal to GPCR LOC51210

GPCR GPR86 Conjugated Antibody

C48382 100ul
EUR 397.00

GPCR RDC1 Conjugated Antibody

C49041 100ul
EUR 397.00

Human GPCR ELISA Kit

EHG0026 96Tests
EUR 521.00

Goat GPCR ELISA Kit

EGTG0026 96Tests
EUR 521.00

Canine GPCR ELISA Kit

ECG0026 96Tests
EUR 521.00

Chicken GPCR ELISA Kit

ECKG0026 96Tests
EUR 521.00

Bovine GPCR ELISA Kit

EBG0026 96Tests
EUR 521.00

D-GPCR Polyclonal Antibody

ES2167-100ul 100ul
EUR 279.00
Description: A Rabbit Polyclonal antibody against D-GPCR from Human. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

D-GPCR Polyclonal Antibody

ES2167-50ul 50ul
EUR 207.00
Description: A Rabbit Polyclonal antibody against D-GPCR from Human. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

Porcine GPCR ELISA Kit

EPG0026 96Tests
EUR 521.00

Rat GPCR ELISA Kit

ERG0026 96Tests
EUR 521.00

Rabbit GPCR ELISA Kit

ERTG0026 96Tests
EUR 521.00

Sheep GPCR ELISA Kit

ESG0026 96Tests
EUR 521.00

Mouse GPCR ELISA Kit

EMG0026 96Tests
EUR 521.00

Monkey GPCR ELISA Kit

EMKG0026 96Tests
EUR 521.00

D-GPCR Polyclonal Antibody

ABP51168-003ml 0.03ml
EUR 158.00
  • Immunogen information: Synthesized peptide derived from the C-terminal region of human D-GPCR at AA range: 210-290
  • Applications tips:
Description: A polyclonal antibody for detection of D-GPCR from Human. This D-GPCR antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human D-GPCR at AA range: 210-290

D-GPCR Polyclonal Antibody

ABP51168-01ml 0.1ml
EUR 289.00
  • Immunogen information: Synthesized peptide derived from the C-terminal region of human D-GPCR at AA range: 210-290
  • Applications tips:
Description: A polyclonal antibody for detection of D-GPCR from Human. This D-GPCR antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human D-GPCR at AA range: 210-290

D-GPCR Polyclonal Antibody

ABP51168-02ml 0.2ml
EUR 414.00
  • Immunogen information: Synthesized peptide derived from the C-terminal region of human D-GPCR at AA range: 210-290
  • Applications tips:
Description: A polyclonal antibody for detection of D-GPCR from Human. This D-GPCR antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human D-GPCR at AA range: 210-290

Anti-D-GPCR Antibody

A12058 100ul
EUR 397.00
Description: Rabbit Polyclonal Antibody for D-GPCR Antibody (OR51E1) detection.tested for WB in Human.

DiscoveryProbe? GPCR Compound Library

L1025-.1 100 uL/well(10 mM solution)
EUR 4736.00

DiscoveryProbe? GPCR Compound Library

L1025-.25 250 uL/well(10 mM solution)
EUR 8518.00

DiscoveryProbe? GPCR Compound Library

L1025-5 5 mg/well
EUR 11070.00

Anti-D-GPCR antibody

STJ92705 200 µl
EUR 197.00
Description: Rabbit polyclonal to D-GPCR.

Anti-GPCR GPR3 Antibody

STJ501253 100 µg
EUR 476.00

Anti-GPCR GPR40 Antibody

STJ501005 100 µg
EUR 476.00

Anti-GPCR SALPR (1F10)

YF-MA18467 100 ug
EUR 363.00
Description: Mouse monoclonal to GPCR SALPR

Anti-GPCR EX33 (5C3)

YF-MA18601 100 ug
EUR 363.00
Description: Mouse monoclonal to GPCR EX33

Anti-GPCR EX33 (5B7)

YF-MA18602 100 ug
EUR 363.00
Description: Mouse monoclonal to GPCR EX33

Anti-GPCR EX33 (1D9)

YF-MA18603 100 ug
EUR 363.00
Description: Mouse monoclonal to GPCR EX33

Anti-GPCR GPR48 (8F6)

YF-MA18780 100 ug
EUR 363.00
Description: Mouse monoclonal to GPCR GPR48

Anti-GPCR GPRC5D (6D9)

YF-MA18788 100 ug
EUR 363.00
Description: Mouse monoclonal to GPCR GPRC5D

Anti-GPCR LGR7 (3E3)

YF-MA11622 100 ug
EUR 363.00
Description: Mouse monoclonal to GPCR LGR7

Anti-GPCR LOC51210 (6D7)

YF-MA19845 100 ug
EUR 363.00
Description: Mouse monoclonal to GPCR LOC51210

Guinea Pig GPCR ELISA Kit

EGG0026 96Tests
EUR 521.00

Anserini GPCR-APJ ELISA Kit

EAG0026 96Tests
EUR 521.00

Anti-GPCR GPR40/FFAR1 Antibody

A01349-2 100ug/vial
EUR 294.00

Anti-GPCR LGR8/RXFP2 Antibody

A04848-1 100ug/vial
EUR 334.00

Anti-LGR6/Gpcr Lgr6 Antibody

A05990 100ul
EUR 397.00
Description: Rabbit Polyclonal LGR6/Gpcr Lgr6 Antibody. Validated in IHC and tested in Human, Mouse, Rat.

Anti-GPCR GPR7/NPBWR1 Antibody

A08247-1 100ug/vial
EUR 294.00

Anti-GPR151/Gpcr 2037 Antibody

A30814 100ul
EUR 397.00
Description: Rabbit Polyclonal GPR151/Gpcr 2037 Antibody. Validated in IF, WB and tested in Mouse, Rat.

Anti-GPR151/Gpcr 2037 Antibody

A14582 100ul
EUR 397.00
Description: Rabbit Polyclonal GPR151/Gpcr 2037 Antibody. Validated in WB and tested in Human, Mouse, Rat.

Anti-GPCR GPR3 Antibody BIOTIN

STJ501254 100 µg
EUR 586.00

Anti-GPCR GPR3 Antibody FITC

STJ501255 100 µg
EUR 586.00

Anti-GPCR GPR40 Antibody BIOTIN

STJ501006 100 µg
EUR 586.00

Anti-GPCR GPR40 Antibody FITC

STJ501007 100 µg
EUR 586.00

anti-5-oxo-ETE GPCR

YF-PA22585 50 ug
EUR 363.00
Description: Mouse polyclonal to 5-oxo-ETE GPCR

Phosphatase Orphan-2 (Recombinant)

20-abx073747
  • EUR 328.00
  • EUR 6397.00
  • EUR 230.00
  • 0
  • 1
  • 2
  • Shipped within 5-10 working days.

Phosphatase Orphan-1 (Recombinant)

20-abx073910
  • EUR 328.00
  • EUR 7358.00
  • EUR 230.00
  • 0
  • 1
  • 2
  • Shipped within 5-10 working days.

DiscoveryProbe? GPCR/G protein-related Compounds Panel

L1009-5 5 mg/well
EUR 6035.00
Description: A wide range of well-characterized bioactive molecules that covers various targets related to GPCR, including adenosine receptor, adrenergic receptor and CXCR etc. Facilitate your research towards the insights of cancer, neurological disorders and heart diseases etc.

Rar-Related Orphan Receptor A (RORA) Antibody

20-abx115045
  • EUR 732.00
  • EUR 398.00
  • 0
  • 1
  • Shipped within 5-10 working days.

Rar-Related Orphan Receptor B (RORB) Antibody

20-abx115046
  • EUR 732.00
  • EUR 398.00
  • 0
  • 1
  • Shipped within 5-10 working days.

Rar-Related Orphan Receptor C (RORC) Antibody

20-abx115047
  • EUR 732.00
  • EUR 398.00
  • 0
  • 1
  • Shipped within 5-10 working days.

RAR Related Orphan Receptor Alpha (RORA) Antibody

20-abx119555
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 0
  • 1
  • 2
  • 3
  • Shipped within 5-10 working days.

Intermediate Filament Family Orphan 1 (IFFO1) Antibody

20-abx113262
  • EUR 732.00
  • EUR 398.00
  • 0
  • 1
  • Shipped within 5-10 working days.

Neuron Derived Orphan Receptor 1 (NOR1) Antibody

20-abx130085
  • EUR 453.00
  • EUR 133.00
  • EUR 1302.00
  • EUR 620.00
  • EUR 342.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • Shipped within 5-7 working days.

RAR Related Orphan Receptor Alpha (RORa) Antibody

20-abx103508
  • EUR 314.00
  • EUR 133.00
  • EUR 815.00
  • EUR 425.00
  • EUR 272.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • Shipped within 5-7 working days.

RAR Related Orphan Receptor Gamma (RORg) Antibody

20-abx103509
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • Shipped within 5-7 working days.

Intermediate Filament Family Orphan 1 (IFFO1) Antibody

abx037159-100ug 100 ug
EUR 391.00
  • Shipped within 5-10 working days.

RAR Related Orphan Receptor Gamma (RORG) Antibody

20-abx013514
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 0
  • 1
  • 2
  • 3
  • Shipped within 5-10 working days.

RAR Related Orphan Receptor Alpha (RORA) Antibody

abx025951-400ul 400 ul
EUR 523.00
  • Shipped within 5-10 working days.

RAR Related Orphan Receptor Alpha (RORA) Antibody

abx025951-80l 80 µl
EUR 286.00
  • Shipped within 5-10 working days.

RAR Related Orphan Receptor Alpha (RORA) Antibody

20-abx005288
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 0
  • 1
  • 2
  • 3
  • Shipped within 5-10 working days.

RAR Related Orphan Receptor Beta (RORB) Antibody

abx027769-400ul 400 ul
EUR 523.00
  • Shipped within 5-10 working days.

RAR Related Orphan Receptor Beta (RORB) Antibody

abx027769-80l 80 µl
EUR 286.00
  • Shipped within 5-10 working days.

Neuron Derived Orphan Receptor 1 (NOR1) Antibody

20-abx173779